Author: Trevor Wilson

Potassium clavulanate is a beta-lactamase inhibitor that increases the bactericidal activity of antibiotics used in combination for the treatment of various bacterial infections. It needs to be taken under medical supervision to avoid any drug-related toxicity. Acute bacterial sinusitis is representing the largest market share in the clinical application segment for the potassium clavulanate market. According to the latest statistics provided by the World Health Organization (WHO), the global incidence rate of acute bacterial sinusitis is 30% worldwide. The disease progression takes place usually after an upper viral respiratory tract…

Amoxicillin sodium is considered as a broad-spectrum antibiotic having potent bactericidal activity. It exerts its pharmacological activity by binding to and inactivating the penicillin-binding proteins which are located in the inner membrane of the bacterial cell wall. It is enlisted in the World Health Organization (WHO) list of essential medicines. Respiratory infections are reigning the clinical application segment for the amoxicillin sodium market. As per the latest information provided by the World Bank data in 2017, pneumonia is responsible for 15% of all the deaths occurring in children below 5…

Amifostine Hydrate was originally developed by the military as a radioprotectant during the event of a nuclear attack. It is basically a prodrug that is dephosphorylated in the tissues by alkaline phosphatase into a free thiol metabolite which is critical in reducing the toxic effects of chemo and radiation therapy on healthy cells. According to the European Society for Medical Oncology (ESMO), head and neck cancer has a global incidence rate of 3.9 and 2.3% per 100,000 people worldwide. Xerostomia is an adverse event associated with radiation therapy which is…

Imidazole is very popular in the biopharmaceutical industry and is frequently used as a buffer for pH ranging from 6.2-7.8 at 25°C. Imidazole buffer is used in several biochemical enzymatic reactions and finds immense application in the detection of proteins by the reverse staining of SDS-PAGE gels. High throughput screening is currently dominating the application segment for the imidazole buffer market. It is widely employed in medicinal chemistry to identify the best stereoisomer of a chemical entity that has an excellent pharmacodynamic and pharmacokinetic drug profile. Optimization of biomolecules is…

Deferiprone is an iron-chelating agent used in the treatment of iron overload associated with blood transfusion and non-transfusion-dependent thalassemia (NTDT). It is available as 500mg & 1000 mg film-coated tablets and 100mg/ml oral solution, which needs to be taken only under medical supervision to negate any possible outcome of drug-related adverse events. Transfusional iron overload is currently reigning the indication segment for the deferiprone market. The human body does not possess any active mechanism for the excretion of iron, which is eventually excreted via sweat, menstruation, and excretion of enterocytes.…

Escitalopram is frequently prescribed by psychiatrists throughout the globe for the treatment of mental illness such as major depressive disorders, generalized anxiety disorders, post-traumatic stress disorders, etc. Least side effect profile, high tolerability, and minimum damage caused to the hepatic cytochrome enzymes have made a highly popular drug in treating mental disorders and are recorded in the World Health Organization (WHO) essential medicines list. Major depression disorders are leading the diseased segment for the Escitalopram market. According to the statistics brought forward by the World Health Organization (WHO), approximately more…